Monday, September 20
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Evening
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Welcome to Friday Harbor; Introduction to conference | Gerald van Belle, Paul Crane, Bill Lee |
Broad overview to AD epi questions for non-AD-epidemiologists: missing data, longitudinal analyses, risk factor analyses, screening, two stage sampling | Gerald van Belle | |
Broad overview of IRT for non-test theorists: θ, I(θ), rational test construction, DIF |
Paul Crane Slides |
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Tuesday, September 21 |
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Morning |
Issues in longitudinal data analysis and the advantages of mixed effects model regression formulations | Richard Kryscio, Brenda Kurland |
Basic introduction to M+ and PARSCALE | Rich Jones, Paul Crane | |
Broad overview of the CHS dataset: design, data elements available, work done to date; Discussion: hypotheses to test: risks for cognitive decline over time in the CHS dataset | Alice Arnold, Annette Fitzpatrick | |
Afternoon |
Work session 1: PARSCALE of the 3MSE | Paul Crane |
Work session 2: set-up of mixed-effects models (other than cognitive scores); testing of assumptions | Richard Kryscio | |
Evening |
Report of PARSCALE group | Paul Crane |
Report of mixed-effects models group | Richard Kryscio | |
Wednesday, September 22 |
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Morning |
Issues in scale co-calibration / score equating | Rich Jones, Paul Crane, Richard Swartz |
Discussion: how should we incorporate SE(theta) into mixed effects regression models? | Gerald van Belle | |
Excel spreadsheet analysis of IRT models | Dan Mungas | |
Afternoon |
Work session 1: M+ analysis | Rich Jones |
Work session 2: incorporation of 3MS theta and SE(theta) into mixed effect regression models | Richard Kryscio | |
Work session 3: MMSE and 3MSE co-calibration / score equating | Paul Crane | |
Item 6 question | Jim Scanlan | |
Evening |
Report of M+ analysis group | Rich Jones |
Report of mixed effects regression group | Richard Kryscio, Marta Mendiondo | |
Report of co-calibration group | Paul Crane | |
Item 6 question group | Jim Scanlan | |
Thursday, September 23 |
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Morning |
Testing IRT assumptions: unidimensionality using MPLUS; local independences | Rich Jones, Paul Crane |
DIF detection using ordinal logistic regression and integration into hypothesis testing; DIF detection using MIMIC formulation | Paul Crane, Rich Jones | |
Missing data and imputation: NORM from Penn State | Richard Kryscio, Marta Mendiondo | |
Afternoon |
Free | |
Evening |
Report of MPLUS group | Rich Jones |
Report of DIFdetect group | Paul Crane | |
Report of mixed effects models group | Richard Kryscio | |
Change with time | Xiaowei Song | |
Friday, September 24 |
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Morning |
Comparison of standard sum scores to DIF-adjusted IRT scores; design of validation analysis | Dan Mungas |
Rash model 2PL comparisions | Deborah Schnipke | |
Issues of diagnosis; optimal screening test properties; use of ROC curves to determine area in which to maximize information | Paul Crane | |
CAMCOG | Rosemary Abbott | |
Discussion: final mixed effects models incorporating all of the things we have considered: item-level DIF incorporation, missing data, 3MSE and MMSE, and how to write up | Richard Kryscio | |
Discussion: Manuscript preparation and dissemination plan | Paul Crane, Rich Jones, Gerald van Belle, Dan Mungas | |
Afternoon |
Work session 1: Validation study of DIF-adjusted IRT scores | |
Work session 2: 3MSE screening test optimization | ||
Work session 3: Mixed effects model group, incorporating DIF-adjusted IRT scores | ||
Evening |
Risk factor group | Jim Scanlan Slides |
M+ working group; APoE effect; growth modeling by subgroups as predictive model; DIF analysis | Rich Jones, Dagmar Amtmann, Rosemary Abbott Jones Slides Amtmann Slides |
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Report of mixed effects model group: final conclusions about risk factors | Richard Kyrscio |
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ROC Group | Paul Crane |
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Saturday, September 25 |
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Morning |
Wrap-up session: lessons learned from conference, future plans | All |